The RSF1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to RSF1. This antibody recognizes Human, and Mouse antigen. The RSF1 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Function: Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex (PubMed:12972596). Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain (PubMed:11944984, PubMed:11788598).
Subunit Structure: Interacts with SMARCA5/SNF2H to form the RSF complex (PubMed:12972596). Identified in a centromere complex containing histones H2A, H2B and H4, and at least CENPA, CENPB, CENPC, CENPT, CENPN, HJURP, SUPT16H, SSRP1 and RSF1 (PubMed:27499292). Also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome (PubMed:11944984, PubMed:11788598)